Human Disease



Our publications and citations can be available at below


27. Jiang, L., T. Li, X. X. Zhang, B. B. Zhang, C. P. Yu, Y. Li, S. X. Fan, X. H. Jiang, T. Khan, Q. M. Hao, P. Xu, D. Nadano, M. Huleihel, E. Lunenfeld, P. J. Wang, Y. W. Zhang* and Q. H. Shi*. RPL10L Is Required for Male Meiotic Division by Compensating for RPL10 during Meiotic Sex Chromosome Inactivation in Mice. Current Biology. Curr Biol. 2017 May 22;27(10):1498-1505.e6. doi: 10.1016/j.cub.2017.04.017. (IF=8.851) [pubmed][PDF]

26. Bukhari, I., G. Y. Li, L. Wang, F. Iqbal, H. Zhang, J. S. Zhu, H. Liu, X. D. Fang, N. M. Al-Daghri, H. J. Cooke, Y. W. Zhang* and X. H. Jiang*. Effects of androgen receptor mutation on testicular histopathology of patient having complete androgen insensitivity. J Mol Histol. 2017 Jun;48(3):159-167. doi: 10.1007/s10735-017-9714-7. (IF=2.362) [pubmed][PDF]

25. Li, G., F. Iqbal, L. Wang, Z. Xu, X. Che, W. Yu, L. Shi, T. Guo, G. Zhou, X. Jiang, H. Zhang, Y. Zhang* and D. Yu* (2017). Meiotic defects and decreased expression of genes located around the chromosomal breakpoint in the testis of a patient with a novel 46,X,t(Y;1)(p11.3;p31) translocation. Int J Mol Med. 2017 Jun 14. doi: 10.3892/ijmm.2017.3029.(IF=2.341) [pubmed][PDF]

24. Changlin Wan Jianing Gao Qiguang zang Rongjun Ban Huan Zhang Yuanwei Zhang (2017). CPSS 2.0: a computational platform update for the analysis of small RNA sequencing data.Bioinformatics. 2017 Feb 8. doi: 10.1093/bioinformatics/btx066. [pubmed][PDF]


23. Yuanwei Zhang, Qiguang Zang, Huan Zhang, Rongjun Ban, Yifan Yang, Furhan Iqbal, Ao Li and Qinghua Shi (2016) DeAnnIso: a tool for online detection and annotation of isomiRs from small RNA sequencing data.Nucl. Acids Res. (08 July 2016) 44 (W1): W166-W175. [pubmed][PDF]

22. Yuanwei Zhang, Yifan Yang, Bo Xu, Qiguang Zang, Wei Zheng, Rongjun Ban, Huan Zhang, Furhan Iqbal, Ao Li and Qinghua Shi (2016) IsomiR Bank: a research resource for tracking IsomiRs. Bioinformatics (2016) 32 (13): 2069-2071 [pubmed][PDF]


21. Zhang, Y., Yu, Z., Ban, R., Zhang, H., Iqbal, F., Zhao, A., Li, A. and Shi, Q. (2015) DeAnnCNV: a tool for online detection and annotation of copy number variations from whole-exome sequencing data. Nucleic acids research, 43, W289-294. [pubmed][PDF]

20. Xu, B., Zhang, Y.W., Tong, X.H. and Liu, Y.S. (2015) Characterization of microRNA profile in human cumulus granulosa cells: Identification of microRNAs that regulate Notch signaling and are associated with PCOS. Mol Cell Endocrinol, 404, 26-36. [pubmed][PDF]

19. Wang, L., Xu, Z., Iqbal, F., Zhong, L., Zhang, Y., Wu, C., Zhou, G., Jiang, H., Bukhari, I., Cooke, H.J. et al. (2015) Decreased XY recombination and disturbed meiotic prophase I progression in an infertile 48, XYY, +sSMC man. Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 23, 267-276. [pubmed][PDF]

18. Wang, L., Iqbal, F., Li, G., Jiang, X., Bukhari, I., Jiang, H., Yang, Q., Zhong, L., Zhang, Y., Hua, J. et al. (2015) Abnormal meiotic recombination with complex chromosomal rearrangement in an azoospermic man. Reproductive biomedicine online, 30, 651-658. [pubmed][PDF]

17. Jiang, X., Ma, T., Zhang, Y., Zhang, H., Yin, S., Zheng, W., Wang, L., Wang, Z., Khan, M., Sheikh, S.W. et al. (2015) Specific deletion of Cdh2 in Sertoli cells leads to altered meiotic progression and subfertility of mice. Biology of reproduction, 92, 79. [pubmed][PDF]

16. Hua, J., Xu, B., Yang, Y., Ban, R., Iqbal, F., Cooke, H.J., Zhang, Y. and Shi, Q. (2015) Follicle Online: an integrated database of follicle assembly, development and ovulation. Database : the journal of biological databases and curation, 2015, bav036. [pubmed][PDF]

15. Shihong Zhu, Y.Y., Mai Zhou. (2015) A note on the empirical likelihood confidence band for hazards ratio with covariate adjustment. Biometrics. [pubmed][PDF]

14. Mai Zhou, Y.Y. (2015) A Recursive Formula for the Kaplan-Meier Estimator with Mean Constraints and Its Application to Empirical Likelihood. Computational Statistics. [PDF]


13. Zhang, H., Jiang, X., Zhang, Y., Xu, B., Hua, J., Ma, T., Zheng, W., Sun, R., Shen, W., Cooke, H.J. et al. (2014) microRNA 376a Regulates Follicle Assembly by Targeting Pcna in Fetal and Neonatal Mouse Ovaries. Reproduction. [pubmed][PDF]

12. Yao, Y.G., Ma, L.L., Jia, Q., Deng, W.K., Liu, Z.X., Zhang, Y.W., Ren, J., Xue, Y., Jia, H.B. and Yang, Q. (2014) Systematic characterization of small RNAome during zebrafish early developmental stages. Bmc Genomics, 15. [pubmed][PDF]

11. Wang, Z., Yin, H., Zhang, Y.W., Feng, Y.K., Yan, Z.F., Jiang, X.H., Bukhari, I., Iqbal, F., Cooke, H.J. and Shi, Q.H. (2014) miR-214-mediated downregulation of RNF8 induces chromosomal instability in ovarian cancer cells. Cell Cycle, 13, 3519-3528. [pubmed]

10. Tong, X.H., Xu, B., Zhang, Y.W., Liu, Y.S. and Ma, C.H. (2014) Research Resources: Comparative MicroRNA Profiles in Human Corona Radiata Cells and Cumulus Oophorus Cells Detected by Next-Generation Small RNA Sequencing. PloS one, 9. [pubmed][PDF]

9. Jiang, X., Zhang, H., Yin, S., Zhang, Y., Yang, W., Zheng, W., Wang, L., Wang, Z., Bukhari, I., Cooke, H.J. et al. (2014) Specific deficiency of Plzf paralog, Zbtb20, in Sertoli cells does not affect spermatogenesis and fertility in mice. Scientific reports, 4, 7062. [pubmed][PDF]

8. Yu, Z., Liu, Y., Shen, Y., Wang, M. and Li, A. (2014) CLImAT: accurate detection of copy number alteration and loss of heterozygosity in impure and aneuploid tumor samples using whole-genome sequencing data. Bioinformatics, 30, 2576-2583. [pubmed][PDF]


7. Zhang, Y.W., Zhong, L.W., Xu, B., Yang, Y.F., Ban, R.J., Zhu, J., Cooke, H.J., Hao, Q.M. and Shi, Q.H. (2013) SpermatogenesisOnline 1.0: a resource for spermatogenesis based on manual literature curation and genome-wide data mining. Nucleic acids research, 41, D1055-D1062. [pubmed][PDF]

6. Yang, Q., Hua, J., Wang, L., Xu, B., Zhang, H., Ye, N., Zhang, Z., Yu, D., Cooke, H.J., Zhang, Y. et al. (2013) MicroRNA and piRNA profiles in normal human testis detected by next generation sequencing. PloS one, 8, e66809. [pubmed][PDF]


5. Zhang, Y.W., Xu, B., Yang, Y.F., Ban, R.J., Zhang, H., Jiang, X.H., Cooke, H.J., Xue, Y. and Shi, Q.H. (2012) CPSS: a computational platform for the analysis of small RNA deep sequencing data. Bioinformatics, 28, 1925-1927. [pubmed][PDF]

4. Chen, D.W., Zhang, Y.W., Yi, Q.Y., Huang, Y., Hou, H.L., Zhang, Y.Y., Hao, Q.M., Cooke, H.J., Li, L., Sun, Q.Y. et al. (2012) Regulation of Asymmetrical Cytokinesis by cAMP during Meiosis I in Mouse Oocytes. PloS one, 7. [pubmed][PDF]

3. Lv, L., Zhang, T.W., Yi, Q.Y., Huang, Y., Wang, Z., Hou, H.L., Zhang, H., Zheng, W., Hao, Q.M., Guo, Z.Y. et al. (2012) Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells. Cell Cycle, 11, 2864-2875. [pubmed][PDF]


2. Zhang, Y.W., Yang, Y.F., Zhang, H., Jiang, X.H., Xu, B., Xue, Y., Cao, Y.X., Zhai, Q., Zhai, Y., Xu, M.Q. et al. (2011) Prediction of novel pre-microRNAs with high accuracy through boosting and SVM. Bioinformatics, 27, 1436-1437. [pubmed][PDF]

1. Xu, B., Hua, J., Zhang, Y., Jiang, X., Zhang, H., Ma, T., Zheng, W., Sun, R., Shen, W., Sha, J. et al. (2011) Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries. PloS one, 6, e16046. [pubmed][PDF]